Because of their potential importance in the treatment of Lyme disease, these articles are being published early (on June 12, 2001). The articles are now available on our Web site (http://www.nejm.org) and will appear in the July 12 issue.

Prophylaxis with Single-Dose Doxycycline for the Prevention of Lyme Disease after an Ixodes scapularis Tick Bite
Robert B. Nadelman and Others
http://www.nejm.org/earlyrelease/feature.asp?strxmlfilename=20010712/01071201

Two Controlled Trials of Antibiotic Treatment in Patients with Persistent Symptoms and a History of Lyme Disease
Mark S. Klempner and Others
http://www.nejm.org/earlyrelease/feature.asp?strxmlfilename=20010712/01071202

Medical Progress: Lyme Disease
Allen C. Steere
http://www.nejm.org/earlyrelease/feature.asp?strxmlfilename=20010712/01071207

Editorial: Doxycycline for Tick Bites -- Not for Everyone
Eugene D. Shapiro
http://www.nejm.org/earlyrelease/feature.asp?strxmlfilename=20010712/01071209

Lyme Disease Health, Hygiene, Illness, Injury